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Chemistry and Biology of Selected Mexican Medicinal Plants

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Progress in the Chemistry of Organic Natural Products 108

Part of the book series: Progress in the Chemistry of Organic Natural Products ((POGRCHEM,volume 108))

Abstract

Herbal medicines are an integral element of alternative medical care in Mexico, and the best testimony to their efficacy and cultural value is their persistence in contemporary Mexican marketplaces where the highest percentages of medicinal and aromatic plants are sold. This chapter summarizes current trends in research on medicinal plants in Mexico, with emphasis on work carried out at the authors’ laboratories. The most relevant phytochemical and pharmacological profiles of a selected group of plants used widely for treating major national health problems are described.

From this contribution, it is evident that in the last five decades a significant amount of research on medicinal plants has been performed by Mexican scientists. Such efforts have led to the publication of many research papers in noted peer-reviewed journals and technical books. The isolation and structural characterization of hundreds of bioactive secondary metabolites have been accomplished, and most importantly, these studies have tended to support the ethnomedical uses of many different species. A multidisciplinary approach for investigating these plants has led to an increased emphasis on areas such as phytopharmacology, phytotoxicology, quality control, regulation, and conservation issues for these valuable resources. The medicinal plants analyzed so far have shown a very broad chemical diversity of their constituents, which have a high potential for exhibiting novel mechanistic effects biologically. The chapter shows also that there is need to conduct additional clinical studies on herbal drugs, in particular because the longstanding traditional evidence for their safety is not always sufficient to assure their rational use. There is also need to move to “omics” approaches for investigating the holistic effect and the influence of groups of phytochemicals on the whole organism. Mexican scientists may be expected to have bright prospects in this regard, which will imbue medicinal plant research with a new dynamism in the future.

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Acknowledgments

This work has been conducted under the auspices of several project grants funded by Consejo Nacional de Ciencia y Tecnología (CONACyT, CB219765 and INFRA268233) and the Dirección General de Asuntos del Personal Académico UNAM (DGAPA, IN217516 and IN213418). R. Mata is very grateful to all her colleagues, postdoctoral fellows, and B.S., M.S., and Ph.D. students, whose collaboration has contributed to the results described in this chapter.

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Authors and Affiliations

  1. Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México, México

    Rachel Mata, Mario Figueroa, Andrés Navarrete & Isabel Rivero-Cruz

Authors
  1. Rachel Mata
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  2. Mario Figueroa
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  3. Andrés Navarrete
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  4. Isabel Rivero-Cruz
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Corresponding authors

Correspondence to Rachel Mata or Mario Figueroa .

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Editors and Affiliations

  1. College of Pharmacy, The Ohio State University, Columbus, OH, USA

    A. Douglas Kinghorn

  2. Institute of Organic Chemistry, Johannes Kepler University, Linz, Austria

    Heinz Falk

  3. UCL School of Pharmacy, University College London, Research, London, UK

    Simon Gibbons

  4. Grad. School of Pharmaceutical Science, Hokkaido University, Fukuoka, Japan

    Jun'ichi Kobayashi

  5. Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan

    Yoshinori Asakawa

  6. School of Pharmaceutical Sciences, South-Central Univ. for Nationalities, Wuhan, China

    Ji-Kai Liu

Appendix

Appendix

Table 3 Selected medicinal plants employed for treating major Mexican health problems
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Mata, R., Figueroa, M., Navarrete, A., Rivero-Cruz, I. (2019). Chemistry and Biology of Selected Mexican Medicinal Plants. In: Kinghorn, A., Falk, H., Gibbons, S., Kobayashi, J., Asakawa, Y., Liu, JK. (eds) Progress in the Chemistry of Organic Natural Products 108. Progress in the Chemistry of Organic Natural Products, vol 108. Springer, Cham. https://doi.org/10.1007/978-3-030-01099-7_1

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