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Taxonomic significance of coumarins in species from the subfamily Mutisioideae, Asteraceae

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Abstract

Asteraceae, the largest family of angiosperms, is divided into 12 subfamilies. The Mutisioideae, which has many representatives in southern South America, is divided into three tribes: Mutisieae, Nassauvieae and Onoserideae. The taxon is highlighted by the production of 5-methylcoumarins, compounds that occur in few families of plants. Within Asteraceae, they are almost restricted to representatives of this subfamily. As the substitution patterns of the 5-methylcoumarins vary in the species of the three different tribes, their occurrence may have a taxonomic significance. Most of the 5-methylcoumarins present terpene moieties connected to the coumarin scaffold. Prenyl and geranyl substituted coumarins are predominant in species of Mutisieae, while in those of tribes Onoserideae and Nassauvieae, compounds chiefly present sesquiterpene units attached to C-3 and C-4 of the α-pyrone moiety. Another interesting observation is the occurrence of furanocoumarins, restrict to species from the tribe Mutisieae. This type of coumarins is rare in Asteraceae. From a biological point of view, the 5-methylcoumarins have been scantily investigated.

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Acknowledgements

This work was supported by financial contributions of Brazilian agencies FAPERGS, CAPES and CNPq.

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Authors and Affiliations

  1. Laboratório de Farmacognosia, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS), Programa de Pós-Graduação em Ciências Farmacêuticas, Avenida Ipiranga 2752, Santana, Porto Alegre, Rio Grande do Sul, 90610-000, Brazil

    Angelica Signor Vestena, Gabriela de Carvalho Meirelles, José Angelo Zuanazzi & Gilsane Lino von Poser

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  1. Angelica Signor Vestena
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  2. Gabriela de Carvalho Meirelles
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  3. José Angelo Zuanazzi
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  4. Gilsane Lino von Poser
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Contributions

Angelica Signor Vestena and Gabriela de Carvalho Meirelles contributed to literature searching and data collection in addition to the manuscript preparation and revision. José Angelo Zuanazzi and Gilsane Lino von Poser contributed to the study concepts and design, as well as to manuscript preparation and revision. All the authors discussed, edited and approved the final version.

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Correspondence to Gilsane Lino von Poser.

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Vestena, A.S., Meirelles, G.d.C., Zuanazzi, J.A. et al. Taxonomic significance of coumarins in species from the subfamily Mutisioideae, Asteraceae. Phytochem Rev 22, 85–112 (2023). https://doi.org/10.1007/s11101-022-09828-x

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  • DOI: https://doi.org/10.1007/s11101-022-09828-x

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