Skip to main content
SpringerLink
Log in

Validation of Traditional Claim of Oxalis debilis Kunth: An Ethnomedicinal Plant from Northeastern Region of India

  • Chapter
  • First Online:
Evidence Based Validation of Traditional Medicines

  • 787 Accesses

Abstract

Ethnomedicinal survey documents the traditional uses of Oxalis debilis Kunth leaves in the management of diarrhea and helminthiasis. In our study, the antidiarrheal and anthelmintic activities were evaluated for ethyl acetate and hydro-alcoholic leaf extracts of O. debilis. Both the leaf extracts exhibited antidiarrheal and anthelmintic activities. The hydro-alcoholic extract exhibited better activity profile than that of ethyl acetate extract. Moreover, the anthelmintic activity was found to be more significant in comparison to the antidiarreal activity for the hydro-alcoholic extract. From phytochemical and TLC studies, the presence of phenolic compounds and flavonoids has been demonstrated in the extracts indicating their possible role in the bioactivity of O. debilis leaves. However, the potent antidiarrheal and anthelmintic activities are claimed with the hydro-alcoholic extract of O. debilis leaves. Our present work justifies the ethnomedicinal claims of O. debilis leaves in the treatment of diarrhea and helminthiasis, particularly in the northeastern region of India.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Abbreviations

CPCSEA:

Committee for the Purpose of Control and Supervision of Experiments on Animals

IAEC:

Institutional Animal Ethics Committee

LOD:

Loss on drying

OECD:

Organisation for Economic Co-operation and Development

SEM:

Standard error of mean

TLC:

Thin-layer chromatography

UV:

Ultraviolet

WHO:

World Health Organization

References

  • Amole OO, Salahdeen HM, Onyeahialam AE (2010) Evaluation of the antidiarrhoeal effect of Lanneawel witschii Hiern (Anacardiaceae) bark extract. Afr J Pharm Pharmacol 4(4):165–169

    Google Scholar 

  • Damiki L, Siva H (2011) Ethnomedicinal plants used for diarrhea by tribals of Meghalaya, Northeast India. Pharmacogn Rev 5(10):147–154

    Article  Google Scholar 

  • Ekor M (2014) The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Front Pharmacol 4:1–10

    Article  Google Scholar 

  • Evans WC (2002) Trease and Evans’ Pharmacognosy. WB Sounders Company Ltd., London

    Google Scholar 

  • Harborne JB (1998) Phytochemical methods: a guide to modern techniques of plant analysis. Chapman & Hall, London

    Google Scholar 

  • Indian Pharmacopoeia (2014) (vol. IV), Published by the Indian Pharmacopoeia Commission (IPC), Ministry of Health and Family Welfare, Government of India, New Delhi

    Google Scholar 

  • Junejo JA, Gogoi G, Zaman K, Islam J, Hazarika G (2016) Phytochemical profiling and toxicological studies of Oxalis debilis Kunth leaves. Int J Green Pharm 10(3):165–171

    CAS  Google Scholar 

  • Junejo JA, Zaman K, Rudrapal M, Mondal P (2014a) Antidiabetic assessment of the hydro-alcoholic leaf extracts of the plant Tetrastigma angustifolia (Roxb.), a traditionally used north-eastern Indian vegetable. Biomed Pharmacol J 7(2):635–644

    Article  Google Scholar 

  • Junejo JA, Zaman K, Rudrapal M, Mondal P, Singh KD, Verma VK (2014b) Preliminary phytochemical and physicochemical evaluation of Carallia brachiata (Lour.) Merr. Leaves. J Appl Pharm Sci 4:123–127

    Article  Google Scholar 

  • Kaneria M, Chanda S (2011) Phytochemical and pharmacognostic evaluation of leaves of Psidium guajava L. (Myrtaceae). Phcog J 3:41–45

    Article  Google Scholar 

  • Kokate CK (1994) Practical Pharmacognosy. Vallabh Prakashan, New Delhi

    Google Scholar 

  • Lourteig A (2000) Oxalis L. Subgenero Monoxalis (Small) Lourt., Oxalis y Trifidus Lourt. Bradea 7:201–629

    Google Scholar 

  • Luo S, Zhang D, Renner S (2006) Oxalis debilis in China: distribution of flower morphs, sterile pollen and polyploidy. Ann Bot 8:459–464

    Article  Google Scholar 

  • Mukherjee PK, Nema NK, Venkatesh P, Debnath PK (2012) Changing scenario for promotion and development of Ayurveda—way forward. J Ethnopharmacol 24:654–342

    Google Scholar 

  • Panda SK, Das D, Tripathy NK (2011) Evaluation of anthelmintic activity of Chlorophytum borivilianum santapau & fernandes. Int J Res Pharm Biomed Sci 2(2):676–679

    Google Scholar 

  • Patiri B, Borah A (2012) Wild edible plants of Assam, NE India. Geetakhi Printers and Publishers, Guwahati

    Google Scholar 

  • Pillai LS, Nair BR (2011) A comparative study of the anthelmintic potential of Cleome viscosa L. and Cleome burmanni W. Indian J Pharm Sci 73(1):98–100

    Article  Google Scholar 

  • Rahman MK, Barua S, Islam MF, Islam MR, Sayeed MA, Parvin MS et al (2013) Studies on the anti-diarrheal properties of leaf extract of Desmodium puchellum. Asian Pac J Trop Biomed 3(8):639–664

    Article  CAS  Google Scholar 

  • Saralaya MG, Patel P, Patel M, Roy SP, Patel AN (2010) Anti-diarrheal activity of methanolic extract of Moringa oleifera lam roots in experimental animal models. Int J Pharm Res 2(2):35–39

    Google Scholar 

  • Shoba FG, Thomas M (2001) Study of antidiarrheal activity of four medicinal plants in castor-oil induced diarrhea. J Ethnopharmacol 76(1):73–76

    Article  CAS  Google Scholar 

  • Singh A, Dubey NK (2012) An ethnobotanical study of medicinal plants in Sonebhadra District of Uttar, Pradesh, India with reference to their infection by foliar fungi. J Med Plants Res 6:2727–2746

    Google Scholar 

  • Sirama V, Kokwaro J, Owuor B, Yusuf A, Kodhiambo M (2015) In-vitro anthelmintic activity of Vernonia amygdalina Del. (asteraceae) roots using adult Haemonchus contortus worms. Int J Pharmacol Res 5(1):1–7

    Google Scholar 

  • Thorn GW, Adams RD, Braunwald E, Isselbacher KJ, Petersdrof RG (1977) Harrison’s principles of internal medicine. McGraw-Hill Book Co., New York

    Google Scholar 

  • Uddin SJ, Sjilpi JA, Alam SM, Alamgir M, Rahman MT, Sarker SD (2005) Antidiarrhoeal activity of the methanol extract of the barks of Xylocarpus moluccensis in castor oil and magnesium sulphate induced diarrhea models in mice. J Ethnopharmacol 101:139–143

    Article  CAS  Google Scholar 

  • Zaman V (1984) Atlas of medical parasitology. ADIS Health Science Press, Sydney

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, India

    Julfikar Ali Junejo, Mithun Rudrapal & Kamaruz Zaman

Authors
  1. Julfikar Ali Junejo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mithun Rudrapal
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kamaruz Zaman
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Kamaruz Zaman .

Editor information

Editors and Affiliations

  1. Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India

    Subhash C. Mandal

  2. NEF College of Pharmacy, Guwahati, Assam, India

    Raja Chakraborty

  3. Faculty of Pharmaceutical Science, Assam down town University, Guwahati, Assam, India

    Saikat Sen

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Junejo, J.A., Rudrapal, M., Zaman, K. (2021). Validation of Traditional Claim of Oxalis debilis Kunth: An Ethnomedicinal Plant from Northeastern Region of India. In: Mandal, S.C., Chakraborty, R., Sen, S. (eds) Evidence Based Validation of Traditional Medicines. Springer, Singapore. https://doi.org/10.1007/978-981-15-8127-4_47

Download citation

Publish with us

Policies and ethics

Search

Navigation