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Bioactive Compounds in Polypodium vulgare L. (Polypodiaceae)

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Bioactive Compounds in Bryophytes and Pteridophytes

Part of the book series: Reference Series in Phytochemistry ((RSP))

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Abstract

Polypodium vulgare L. (Polypodiaceae), a fern with a wide distribution worldwide and in different continents, is also known as a polypody due to the shape of its frond as feet; since ferns are poorly studied from a phytochemical and ethnopharmacological perspective, these species may also represent a source of bioactive compounds with interesting properties for potential pharmacological, cosmetic, or agrochemical applications. Polypodium vulgare has been used traditionally for medicinal and food purposes. In certain regions, the young fronds are used as edible foods and traditional uses include this species as a medicinal plant with hepatoprotective, wound-healing, expectorant, or laxative properties. According to chemical studies, two main classes of phytochemicals have been detected: polyphenols and steroids. Among polyphenols, caffeoylquinic acids such as chlorogenic acid and flavonoids such as rutin have been quantified. Among steroids, some studies reveal the presence of osladin, a compound with sweetener capacity.

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Abbreviations

3T3:

NIH 3T3 mouse fibroblast cell line

DPPH:

2,2-diphenyl-1-picrylhydrazyl

EMA:

European Medicines Agency

EU:

European Union

HaCaT:

Spontaneously immortalized human keratinocyte cell line

HPLC-DAD:

High-performance liquid chromatography-diode array detector

HPLC-MS/MS:

High-performance liquid chromatography-tandem mass spectrometry

ORAC:

Oxygen Radical Absorbance Capacity

PLE:

Aqueous extract of Polypodium leucotomos fronds

PVM:

Methanolic extract of Polypodium vulgare L. fronds

ROS:

Reactive Oxygen Species

UVA:

Ultraviolet A

WHO:

World Health Organization

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Acknowledgments

Universidad San Jorge and Gobierno de Aragón are thanked for financial and technical support (B44_20D-Phyto-Pharm group).

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Authors and Affiliations

  1. Department of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, Villanueva de Gállego (Zaragoza), Spain

    Adrià Farràs & Víctor López

  2. Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Sciences, Universitat de Barcelona, Barcelona, Spain

    Adrià Farràs & Montserrat Mitjans

Authors
  1. Adrià Farràs
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  2. Montserrat Mitjans
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  3. Víctor López
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Correspondence to Víctor López .

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Editors and Affiliations

  1. Department of Botany, Karnatak University, Dharwad, Karnataka, India

    Hosakatte Niranjana Murthy

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Farràs, A., Mitjans, M., López, V. (2023). Bioactive Compounds in Polypodium vulgare L. (Polypodiaceae). In: Murthy, H.N. (eds) Bioactive Compounds in Bryophytes and Pteridophytes. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-030-97415-2_22-1

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  • DOI: https://doi.org/10.1007/978-3-030-97415-2_22-1

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